Product Info Summary
SKU: | M01016 |
---|---|
Size: | 0.1 mg |
Reactive Species: | Human |
Host: | Mouse |
Application: | Flow Cytometry, IP, IHC-P |
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Product info
Product Name
Anti-Hu CD98 Purified SLC7A5 Monoclonal Antibody
View all SLC7A5/LAT1 Antibodies
SKU/Catalog Number
M01016
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Hu CD98 Purified SLC7A5 Monoclonal Antibody (Catalog# M01016). Tested in Flow Cytometry, IP, IHC-P application(s). This antibody reacts with Human.
Storage & Handling
Store at 2-8°C. Do not freeze.
Cite This Product
Anti-Hu CD98 Purified SLC7A5 Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M01016)
Host
Mouse
Contents
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Clonality
Monoclonal
Clone Number
MEM-108
Isotype
Mouse IgG1
Immunogen
RAJI human Burkitt's lymphoma cell line. The antibody MEM-108 reacts with an extracellular epitope of CD98, a 125 kDa disulfide-linked heterodimer (80 kDa glycosylated heavy chain + 45 kDa non-glykosylated light chain). CD98 is expressed on T lymphocytes (upon activation) and activated NK cells; it is also present at low levels on B lymphocytes, NK cells, monocytes and platelets.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
M01016 is reactive to SLC7A5 in Human
Applications
M01016 is guaranteed for Flow Cytometry, IP, IHC-P Boster Guarantee
Observed Molecular Weight
42 kDa
Calculated molecular weight
55.01kDa
Background of SLC7A5/LAT1
CD98 (4F2) is a type II transmembrane glycoprotein which serves as the heavy chain of the heterodimeric amino acid transporters (HATs). CD98, linked to various light chains by disulfide bond, is responsible for cell surface expression and basolateral localization of this transporter complex in polarized epithelial cells and also interacts with beta1 integrins and increases their affinity for ligand. Besides its roles in amino acid transport, CD98 is thus involved in cell fusion and activation. It is implicated in regulation of cellular differentiation, growth and apoptosis.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Flow cytometry: 4 μg/ml.
Immunohistochemistry (paraffin sections): 10 μg/ml; positive tissue: liver.
Validation Images & Assay Conditions
Click image to see more details
Figure 1. Flow Cytometry validation of SLC7A5 using Anti-Hu CD98 Purified SLC7A5 Monoclonal Antibody (M01016).
Flow cytometry analysis (surface staining) of human peripheral blood monocytes with anti-human CD98 (MEM-108) purifiedProtein Target Info & Infographic
Gene/Protein Information For SLC7A5 (Source: Uniprot.org, NCBI)
Gene Name
SLC7A5
Full Name
Large neutral amino acids transporter small subunit 1
Weight
55.01kDa
Superfamily
amino acid-polyamine-organocation (APC) superfamily
Alternative Names
4F2 LC; 4F2LC; CD98; CD98lc; D16S469EL-type amino acid transporter 1; E16; Integral membrane protein E16; large neutral amino acids transporter 1; large neutral amino acids transporter small subunit 1; LAT1; LAT1hLAT1; MPE16; MPE16CD98 light chain; SLC7A5; sodium-independent neutral amino acid transporter LAT1,4F2LC; solute carrier family 7 (cationic amino acid transporter, y+ system), member 5,4F2 light chain; Solute carrier family 7 member 5; TA1; y+ system cationic amino acid transporter SLC7A5 4F2LC, CD98, D16S469E, E16, LAT1, MPE16 solute carrier family 7 member 5 large neutral amino acids transporter small subunit 1|4F2 light chain|CD98 light chain|L-type amino acid transporter 1|integral membrane protein E16|sodium-independent neutral amino acid transporter LAT1|solute carrier family 7 (amino acid transporter light chain, L system), member 5|solute carrier family 7 (cationic amino acid transporter, y+ system), member 5
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on SLC7A5, check out the SLC7A5 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for SLC7A5: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Hu CD98 Purified SLC7A5 Monoclonal Antibody (M01016)
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No publications found for M01016
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